Executive summary. Eligibility analysis needs the applicable program policy, the patient and encounter context, the drug movement, and retained records behind each determination.

Definition

340B eligibility is the determination, under program requirements and policy, of whether a dispense or drug use may be associated with 340B program inventory.

Preserve the relevant context

Keep the facility, covered entity, patient, encounter, prescriber, location, drug, and date context your policy and the program rules require. Eligibility cannot be inferred from the presence of a drug on a shelf.

The evidence needed varies with the covered entity and the arrangement. Set the policy with qualified program and legal guidance.

Make exceptions visible

Where required context is absent or contradictory, route the transaction for review rather than assigning a program status quietly. The exception should carry the missing or conflicting condition with it.

Retain the policy version used for each determination. Rules and organizational arrangements change, and a decision has to be read against the version that governed it.

Frequently asked questions

Can a 340B decision be made from claim data alone?

Often not. Program eligibility can depend on clinical, entity, location, and policy context that the claim never carries.

Referenced standards and further reading

Related articles

Understand 340B inventory accumulation methods →

Diversion prevention is a control system →

Attergo guide: 340B program basics →

Revision history

2026-08-05 · 1.0, initial public reference · Published by Ryan Stringer.